Search results for "Size reduction"
showing 6 items of 6 documents
Design of enzyme-mediated controlled release systems based on silica mesoporous supports capped with ester-glycol groups
2012
[EN] An ethylene glycol-capped hybrid material for the controlled release of molecules in the presence of esterase enzyme has been prepared. The final organic-inorganic hybrid solid S1 was synthesized by a two-step procedure. In the first step, the pores of an inorganic MCM-41 support (in the form of nanoparticles) were loaded with [Ru(bipy) 3]Cl 2 complex, and then, in the second step, the pore outlets were functionalized with ester glycol moieties that acted as molecular caps. In the absence of an enzyme, release of the complex from aqueous suspensions of S1 at pH 8.0 is inhibited due to the steric hindrance imposed by the bulky ester glycol moieties. Upon addition of esterase enzyme, del…
Gastropod evidence against the Early Triassic Lilliput effect
2010
4 pages; International audience; Size reduction in the aftermath of the Permian-Triassic mass extinction event has repeatedly been described for various marine organisms, including gastropods (the Lilliput effect). A Smithian gastropod assemblage from Utah, USA, reveals numerous large-sized specimens of different genera as high as 70 mm, the largest ever reported from the Early Triassic. Other gastropods reported from Serbia and Italy are also as large as 35 mm. Size frequency distributions of the studied assemblages indicate that they were not unusually small when compared with later Mesozoic and modern faunas. The occurrence of large-sized gastropods less than 2 Ma after the Permian-Trias…
Physicochemical and technological properties of beef burger as influenced by the addition of pea fibre
2019
This study aimed to evaluate the physicochemical characteristics and sensory attributes of beef burgers with the addition of pea fibre as a partial substitute of meat or fat. Three formulations were prepared: control (CON) – similar to the commercial formulation; fibre/less meat (FLM)—5% meat reduction and addition of 1% pea fibre; fibre/less fat (FLF)—7% fat reduction and addition of 1% pea fibre. Non‐significant differences were obtained for pH, colour parameters (L* and b*), texture profile, cooking loss and size reduction among formulations. Moreover, sensory analysis with consumers of beef burgers did not indicate differences among the formulations for all the analysed attributes. Ther…
Photochemical Size Reduction of CdSe and CdSe/ZnS Semiconductor Nanoparticles Assisted by nπ* Aromatic Ketones
2009
A novel effect of n pi* aromatic ketones on the quantum dots optical properties is reported. By controlling experimental conditions such as time of irradiation, presence of air in the media, hydrogen donor capacity of the solvent, and irradiation wavelength, core and core-shell CdSe QDs can be resized as convenient.
Engineering of Nanofibrous Amorphous and Crystalline Solid Dispersions for Oral Drug Delivery
2018
Poor aqueous solubility (<0.1 mg/mL) affects a significant number of drugs currently on the market or under development. Several formulation strategies including salt formation, particle size reduction, and solid dispersion approaches have been employed with varied success. In this review, we focus primarily on the emerging trends in the generation of amorphous and micro/nano-crystalline solid dispersions using electrospinning to improve the dissolution rate and in turn the bioavailability of poorly water-soluble drugs. Electrospinning is a simple but versatile process that utilizes electrostatic forces to generate polymeric fibers and has been used for over 100 years to generate synthet…
Efficacy of ozonized water for the treatment of erosive oral lichen planus : a randomized controlled study
2020
Background Management of erosive Oral Lichen Planus (eOLP) is challenging. Currently, topical corticosteroids are widely used as first-line therapy, but they might be associated with side-effects and incomplete clinical response. Among non-pharmacological strategies, ozone at low medical concentration has proven to induce a mild activation of protective anti-oxidant pathways, thus exerting therapeutic effects in many inflammatory diseases. The aim of this randomized controlled study was to investigate the effectiveness of ozonized water in association with conventional topical corticosteroids for the treatment of eOLP. Material and Methods Fifty-one patients were included in the study and r…